Directions to Our Hotel by Mayo Clinic

The Kahler Grand Hotel is connected to Mayo Clinic via two climate-controlled pedestrian walkways: an above-ground skyway and underground concourse. The hotel by Mayo Clinic is in the heart of downtown Rochester, with a great variety of shopping and dining onsite.

The Kahler Grand Hotel

20 SW Second Avenue
Rochester, MN 55902
Phone: 507-280-6200
Fax: 507-285-2775


From Highway 63 N

  • Turn left on Center Street
  • Go 1 block and turn left on 2nd Avenue
  • The hotel is on the east side of the street

Book your stay today at one of the top Mayo Clinic hotels.